Nucleotides

Edited By: MENIIT Team | Updated on Jul 13, 2024 09:23 AM GMT+0000 | # Zoology

Nucleotides forms the monomer of nucleic acids i.e. DNA and RNA. A nucleotide is composed of three components:

(A) A phosphate group

(B) Pentose sugar

(C) Nitrogenous bases

(A) Phosphate group

phosphate-group

(B) Pentose sugar: RNA has ribose as base sugar while DNA shows the presence of Deoxyribose.

pentose-sugar

(C) Nitrogenous bases : They are of two types, purines and pyrimidines.

Purines are 9-membered double ring, nitrogen bases which posses nitrogen at 1, 3, 7 and 9 positions, e.g. adenine (A), guanine (G).

Pyrimidines are 6-membered nitrogen bases that contain nitrogen at 1 and 3 positions, e.g., Cytosine (C), Thymine (T), Uracil (U).

Table of Contents

Nucleoside

They are compounds formed from a nitrogen base and pentose sugar. Nitrogen base combines with pentose sugar molecule at its carbon atom 1′ in a N-glycosidic bond (C–N–C) by one of its nitrogen atom (1 in pyrimidines and 9 in purines).

nucleoside

Nucleotide

A nucleotide is a compound made of a nitrogen base, a pentose sugar and phosphate, Phosphate combines with sugar at its 5′ carbon with ester bond, sugar with nitrogen base at carbon 1 while nitrogen base is usually attached to sugar at its 9 (purine) or 1 (pyrimidine) atom.

nucleotide

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